| 英文名稱 | Gambogic acid |
|---|---|
| 中文名稱 | 藤黃酸/R,S-藤黃酸/藤黃酸A/β-藤黃素/(Z)-4-((1S,3aR,5S,11R,14aS)-8-羥基-2,2,11-三甲基-13-(3-甲基丁-2-烯-1-基)-11-(4-甲基戊-3-烯-1-基)-4,7-二氧代-1,2,5,7-四氫-11H-1,5-甲橋呋喃并[3,2-g]吡喃并[3,2-b]氧雜蒽-3a(4H)-基)-2-甲基丁-2-烯酸 |
| CAS號 | 2752-65-0 |
| 分子式 | C38H44O8 |
| 分子量 | 628.75 |
| 外觀 | 橙黃色粉末 |
| 熔點 | 78-90 °C |
| 沸點 | 808.9±65.0 °C | Condition: Press: 760 Torr |
| 酸度系數(shù)pKa | 4.58±0.36 | Condition: Most Acidic Temp: 25 °C |
WKQ-0000551
中文名稱：藤黃酸
中文別名：R,S-藤黃酸；藤黃酸A；β-藤黃素；(Z)-4-((1S,3aR,5S,11R,14aS)-8-羥基-2,2,11-三甲基-13-(3-甲基丁-2-烯-1-基)-11-(4-甲基戊-3-烯-1-基)-4,7-二氧代-1,2,5,7-四氫-11H-1,5-甲橋呋喃并[3,2-g]吡喃并[3,2-b]氧雜蒽-3a(4H)-基)-2-甲基丁-2-烯酸
英文名稱：Gambogic acid
英文別名：1,5-Methano-1H,3H,11H-furo[3,4-g]pyrano[3,2-b]xanthene-1-crotonic acid, 3a,4,5,7-tetrahydro-8-hydroxy-α,3,3,11-tetramethyl-13-(3-methyl-2-butenyl)-11-(4-methyl-3-pentenyl)-7,15-dioxo-, (Z)- (8CI);2-Butenoic acid, 2-methyl-4-[(1R,3aS,5S,11R,14aS)-3a,4,5,7-tetrahydro-8-hydroxy-3,3,11-trimethyl-13-(3-methyl-2-butenyl)-11-(4-methyl-3-pentenyl)-7,15-dioxo-1,5-methano-1H,3H,11H-furo[3,4-g]pyrano[3,2-b]xanthen-1-yl]-, (2Z)- (9CI);2-Butenoic acid, 2-methyl-4-[3a,4,5,7-tetrahydro-8-hydroxy-3,3,11-trimethyl-13-(3-methyl-2-butenyl)-11-(4-methyl-3-pentenyl)-7,15-dioxo-1,5-methano-1H,3H,11H-furo[3,4-g]pyrano[3,2-b]xanthen-1-yl]-, [1R-[1α,1(Z),3aβ,5α,11β,14aS*]]-;Gambogic acid (7CI);(2Z)-2-Methyl-4-[(1R,3aS,5S,11R,14aS)-3a,4,5,7-tetrahydro-8-hydroxy-3,3,11-trimethyl-13-(3-methyl-2-buten-1-yl)-11-(4-methyl-3-penten-1-yl)-7,15-dioxo-1,5-methano-1H,3H,11H-furo[3,4-g]pyrano[3,2-b]xanthen-1-yl]-2-butenoic acid;(-)-Gambogic acid;R-Gambogic acid;UI1907;β-Guttiferin;
分子式：C38H44O8
分子量：628.75
CAS號：2752-65-0
純度：HPLC≥98%
熔點：78-90 °C
沸點：808.9±65.0 °C | Condition: Press: 760 Torr
密度：1.29±0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr
酸系度數(shù)：4.58±0.36 | Condition: Most Acidic Temp: 25 °C
儲存條件：-20℃，干燥、避光、密封
規(guī)格：5mg10mg20mg50mg100mg500mg1g2g等應(yīng)客戶需求包裝
供應(yīng)單位：四川省維克奇生物科技有限公司
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| Cascade-responsive nano-assembly for efficient photothermal-chemo synergistic inhibition of tumor metastasis by targeting cancer stem cells | ||
| 來源：SCI：BIOMATERIALS | 作者：Xianqi Zhu | 備注：影響因子：12.479 |
| 引用描述 | ||
Gambogic acid was purchased from Sichuan Weikeqi Biological Technology Co. Ltd. 4-Dimethylaminopyridine (DMAP), N-hydroxy succinimide (NHS), dicyclohexyl carbodiimide (DCC), 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC), 4-carboxybenzaldehyde, Pd2 (dba)3, sodium tert-butoxide, tri-tert-butyl phosphine, croconic acid | ||
| Mucoadhesive nanoparticles based on ROS activated gambogic acid prodrug for safe and efficient intravesical instillation chemotherapy of bladder cancer | ||
| 來源：SCI：JOURNAL OF CONTROLLED RELEASE | 作者：Xin Xu | 備注：影響因子：7.727 |
| 引用描述 | ||
Gambogic acid was purchased from Sichuan Weikeqi Biological Technology Co. Ltd. 4-Dimethylaminopyridine (DMAP), N-hydroxy succinimide (NHS), dicyclohexyl carbodiimide (DCC), 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC), 4-hydroxybenzylboronic acid pinacol ester, chitosan (Mw = 5 kDa) | ||
| Enhanced Anticancer Efficacy of Dual Drug-Loaded Self-Assembled Nanostructured Lipid Carriers Mediated by pH-Responsive Folic Acid and Human-Derived Cell Penetrating Peptide dNP2 | ||
| 來源：SCI：Pharmaceutics | 作者：Zhe Ma | 備注：影響因子：6.321 |
| 引用描述 | ||
PTX with a purity of more than 98% was acquired from Shanghai yuanye Bio-Technology Co., Ltd. (Shanghai, China); GA with a purity of more than 98% was purchased from Sichuan Weikeqi Bio-Tech Co. Ltd. (Chengdu, China); Compritol 888 ATO (Glycerol behenate) was obtained from Gattefossé (St. Priest, France); Myrj 52 (Polyethylene Glycol (40) Monostearate) was obtained from Saint-Priest Cedex, France; MCT 812 (Miglyol? 812) was purchased from Beijing Feng Li Jing Qi Trading Co., Ltd. | ||
| Dimeric c(RGD) peptide conjugated nanostructured lipid carriers for efficient delivery of Gambogic acid to breast cancer | ||
| 來源：SCI：International Journal of Nanomedicine | 作者：Dereje Kebebe | 備注：影響因子：4.471 |
| 引用描述 | ||
Gambogic acid (GA) (HPLC >98%) was purchased from Weikeqi Bio-Tech Co. Ltd, China; Compritol 888 ATO (Glycerol behenate) and Myrj 52 (Polyethylene Glycol (40) Monostearate) were obtained from Saint-Priest Cedex, France; MCT 812 (Miglyol? 812) was purchased from Beijing Feng Li Jing Qi Trading Co., Ltd. China; LIPOID S-100 (Soybean Lecithin) was obtained from Shanghai Dong Shang Industrial Co., Ltd, China | ||
| Synergistic antitumor efficacy of doxorubicin and gambogic acid-encapsulated albumin nanocomposites | ||
| 來源：SCI：COLLOIDS AND SURFACES B-BIOINTERFACES | 作者：Zhoujiang Chen | 備注：影響因子：4.389 |
| 引用描述 | ||
BSA (96%) was acquired from Aladdin Bio-Chem Technology Co. Ltd. (Shanghai, China). GA was procured from Weikeqi Biological Technology Co., Ltd (Chengdu, China). Doxorubicin hydrochloride (DOX·HCl) was obtained from Meryer Chemical Technology Co., Ltd (Shanghai, China). | ||
| Cell penetrating peptides functionalized gambogic acid-nanostructured lipid carrier for cancer treatment | ||
| 來源：SCI：DRUG DELIVERY | 作者：Rui Huang | 備注：影響因子：3.095 |
| 引用描述 | ||
GA with a purity of more than 98% was purchased from Sichuan Weikeqi Bio-Tech Co. Ltd (Chengdu, China). RGERPPR and CRGDRGPDC peptides (Supplementary Figure S1) were synthesized by Chinapeptide Biotech Co. Ltd. (Shanghai, China). DSPE–PEG2000–NHS was purchased from Shanghai Advanced Vehicle Technology Pharmaceutical Co. Ltd. (Shanghai, China). | ||
